Molecules with the same chemical formula but different structural compositions are called tautomers. This transition can be triggered locally by the injection of a tunneling current from a STM tip. In a recent publication we have studied if and to what extent engineered atomic-scale nanostructures can be utilized for the manipulation of remote STM-induced single molecule tautomerization, i.e., by injecting a current not into the molecule to be switched but at a distance of a few nanometers into the surrounding substrate. The experiments nicely show how walls or ellipses engineered from single Ag atoms domp or enhance tautomerization. The results have been published in Nano Lett. 17, 5106 (2017).