The closest airports are Frankfurt/Main and Nürnberg.
From Frankfurt airport to Würzburg the train takes about 90 minutes and departs every hour.
From Nürnberg, the train takes between 1 and 2 hours and departs almost every 30
In Würzburg, many University buildings, sights and shopping facilities are within walking distance from the city centre.
Moreover, the trams and buses of the local transportation company network in Franconia (VVM) are a good option to reach your goals quickly without worrying for parking spaces. Current timetables can be downloaded at the webpage of the transportation company network.